top of page
Symbolic image of protein analysis

Size exclusion chromatography (SEC/GFC) in aqueous solvents

Separation of proteins, other large biomolecules and polymers

Product overview

Shodex PROTEIN Series_square.jpg



  • Silica-based columns for aqueous SEC (GFC) analysis

  • Suitable for the analysis of proteins and enzymes

  • Fulfills USP L20, L33, and L59 requirements

  • LW-803: Pore size specifically controlled for analyzing proteins with a molecular weight of several hundred of thousand for high performance analysis of antibody drugs and various proteins

  • Also smaller columns with smaller particles sizes available

OHpak SB-800 series

OHpak LB-800 series

  • Polymer-based columns for aqueous SEC (GFC) analysis

  • Supports a wide range of molecular weight sample analysis

  • For modified proteins, PEGs, polysaccharides (hyaluronic acid, alginates), surfactants

  • SB-807 HQ: Column for the analysis of water-soluble ultra high molecular weight polymers, large particle-size gel prevents shear degradation of polymers

  • LB-800: Low column bleeding allows its use with light scattering detectors (MALS)

Shodex OHpak SB Series_square.jpg
Shodex Asahipak GS and GF Series_square.

Asahipak GS series (multi mode)

  • SEC is the main separation mode

  • With the choice of eluent, the column provides multimode features of reversed phase, HILIC, and ion exchange modes to SEC

  • Suitable for the separation of peptides or nucleic acids with similar molecular weights

  • Suitable for desalting samples or substituting buffer in protein analysis

Ashipak GF series (multi solvent)


  • Polymer-based SEC columns with high solvent durability

  • Works well with both aqueous and organic solvents

Shodex Asahipak GS and GF Series_square.

Column Selection Proteins, Peptides, Amino Acids

Column Selection Proteins Peptides Amino Acids.jpg

Column Selection Polymers

Column Selection Polymers.jpg

Tutorial video

bottom of page