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Size exclusion chromatography (SEC/GFC) in aqueous solvents

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Separation of proteins, other large biomolecules and polymers

Product overview

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PROTEIN KW series

PROTEIN LW series

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  • Silica-based columns for aqueous SEC (GFC) analysis

  • Suitable for the analysis of proteins and enzymes

  • Fulfills USP L20, L33, and L59 requirements

  • LW-803: Pore size specifically controlled for analyzing proteins with a molecular weight of several hundred of thousand for high performance analysis of antibody drugs and various proteins

  • Also smaller columns with smaller particles sizes available

OHpak SB-800 HQ series

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  • Polymer-based columns for aqueous SEC (GFC) analysis

  • Supports a wide range of molecular weight sample analysis

  • For modified proteins, PEGs, polysaccharides (hyaluronic acid, alginates), surfactants

  • SB-807 HQ: Column for the analysis of water-soluble ultra high molecular weight polymers, large particle-size gel prevents shear degradation of polymers

  • Also available in preparative dimensions

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Shodex OHpak LB Series_square.jpg

OHpak LB-800 series [for MALS]

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  • Same like OHpak SB-800 HQ series, but for Light Scattering detectors

  • Higher crosslinking for ultra-low bleeding for better chromatograms in particle-sensitive detectors

  • Polymer-based columns for aqueous SEC (GFC) analysis

  • Supports a wide range of molecular weight sample analysis

  • For modified proteins, PEGs, polysaccharides (hyaluronic acid, alginates), surfactants

Asahipak GS series (multi mode)

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  • SEC is the main separation mode

  • With the choice of eluent, the column provides multimode features of reversed phase, HILIC, and ion exchange modes to SEC

  • Suitable for the separation of peptides or nucleic acids with similar molecular weights

  • Suitable for desalting samples or substituting buffer in protein analysis

Shodex Asahipak GS and GF Series_square.
Shodex Asahipak GS and GF Series_square.

Ashipak GF series (multi solvent)

 

  • Polymer-based SEC columns with high solvent durability

  • Works well with both aqueous and organic solvents

UB-50 and UB-100 for bio-nanoproducts

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  • separation by size for biomolecules above and below 50 nm

  • bio-nanoproduct analysis and preparative use

  • for viruses, virus-like particles (VLPs), and exosomes

  • low back pressure and high separation efficiency

  • high stability against basic solvents and other chemicals commonly used in bioprocessing

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Column Selection Proteins, Peptides, Amino Acids

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Column Selection Polymers

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Tutorial video

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