Shodex ODP2 Series_43.jpg

ODP2 columns

with small pores

The robust polymer-based RP column for small molecules in protein matrix

Download the product overview (pdf)

Product information

 

ODP2 HP columns

The Shodex ODP2 HP series offers polymer–based columns for reversed phase chromatography. The efficiency of ODP2 HP columns is improved over most resin-based columns and is comparable with that of silica-based ODS columns. They don't contain C18 functional groups, the separation comes from the particle itself.


ODP2 HP has a better retention of highly polar substances compared to most general purpose silica-based C18 columns. Silica-based C18 ODS columns are susceptible to protein adsorption, resulting in degradation of the column. ODP2 HP is designed to exclude protein and thus, ODP2 HP can be used for analysis of drugs in biological samples containing protein without rapid column deterioration. As ODP2 HP can be used with low salt concentration without loss of peak shapes, it is excellent for LC/MS analysis.

  • Provides a large theoretical plate number nearly twice as much as generally available polymer-based
    reversed phase columns do

  • Offers enhanced retention of high polar substances compared to ODS columns

  • Suitable for the analysis of small molecules such as pharmaceuticals in the presence of protein matrix

  • Ideal for LC/MS analysis of high polar compounds

  • Fulfills USP L39 requirements

The material is completely silanol-free and therefore proteins are not adsorbed in the column.

RP comparison.jpg

Product overview

Product code
Product name
Separation
Functional group
Gel material
Plates per column
Particle size
Pore size
Size (ID x length)
Housing material
F7622004
ODP2 HP-2B
RP
-
Polyhydroxy-methacrylate
≥ 3,000
5 µm
40 Å
2.0 x 50 mm
steel
F7622005
ODP2 HP-2D
RP
-
Polyhydroxy-methacrylate
≥ 7,000
5 µm
40 Å
2.0 x 150 mm
steel
F6714011
ODP2 HPG-2A
RP
-
Polyhydroxy-methacrylate
(guard)
5 µm
-
2.0 x 50 mm
steel
F7622001
ODP2 HP-4B
RP
-
Polyhydroxy-methacrylate
≥ 3,500
5 µm
40 Å
4.6 x 50 mm
steel
F7622002
ODP2 HP-4D
RP
-
Polyhydroxy-methacrylate
≥ 10,000
5 µm
40 Å
4.6 x 150 mm
steel
F7622003
ODP2 HP-4E
RP
-
Polyhydroxy-methacrylate
≥ 17,000
5 µm
40 Å
4.6 x 250 mm
steel
F6714010
ODP2 HPG-4A
RP
-
Polyhydroxy-methacrylate
(guard)
5 µm
-
2.0 x 50 mm
steel

Product details

Product name
Maximum pressure
Maximum flow rate
Temperature range
pH range
Salt concentration
Shipping solvent
USP
ODP2 HP-2B
12 MPa (120 bar)
0.3 mL/min
20 to 60°C
2 to 12
≤ 0.1 M
H2O/ACN=55/45
L39
ODP2 HP-2D
15 MPa (150 bar)
0.3 mL/min
20 to 60°C
2 to 12
≤ 0.1 M
H2O/ACN=55/45
L39
ODP2 HPG-2A
-
-
20 to 60°C
2 to 12
≤ 0.1 M
H2O/ACN=55/45
L39
ODP2 HP-4B
15 MPa (150 bar)
1.5 mL/min
20 to 60°C
2 to 12
≤ 0.1 M
H2O/ACN=55/45
L39
ODP2 HP-4D
15 MPa (150 bar)
1.5 mL/min
20 to 60°C
2 to 12
≤ 0.1 M
H2O/ACN=55/45
L39
ODP2 HP-4E
15 MPa (150 bar)
1.0 mL/min
20 to 60°C
2 to 12
≤ 0.1 M
H2O/ACN=55/45
L39
ODP2 HPG-4A
-
-
20 to 60°C
2 to 12
≤ 0.1 M
H2O/ACN=55/45
L39

Product info