ODP2 columns
with small pores
The robust polymer-based RP column for small molecules in protein matrix
Download the product overview (pdf)
Product information
ODP2 HP columns
The Shodex ODP2 HP series offers polymer–based columns for reversed phase chromatography. The efficiency of ODP2 HP columns is improved over most resin-based columns and is comparable with that of silica-based ODS columns. They don't contain C18 functional groups, the separation comes from the particle itself.
ODP2 HP has a better retention of highly polar substances compared to most general purpose silica-based C18 columns. Silica-based C18 ODS columns are susceptible to protein adsorption, resulting in degradation of the column. ODP2 HP is designed to exclude protein and thus, ODP2 HP can be used for analysis of drugs in biological samples containing protein without rapid column deterioration. As ODP2 HP can be used with low salt concentration without loss of peak shapes, it is excellent for LC/MS analysis.
-
Provides a large theoretical plate number nearly twice as much as generally available polymer-based
reversed phase columns do -
Offers enhanced retention of high polar substances compared to ODS columns
-
Suitable for the analysis of small molecules such as pharmaceuticals in the presence of protein matrix
-
Ideal for LC/MS analysis of high polar compounds
-
Fulfills USP L39 requirements
The material is completely silanol-free and therefore proteins are not adsorbed in the column.
Product overview
Product code | Product name | Separation | Functional group | Gel material | Plates per column | Particle size | Pore size | Size (ID x length) | Housing material |
|---|---|---|---|---|---|---|---|---|---|
F7622004 | ODP2 HP-2B | RP | - | Polyhydroxy-methacrylate | ≥ 3,000 | 5 µm | 40 Å | 2.0 x 50 mm | steel |
F7622005 | ODP2 HP-2D | RP | - | Polyhydroxy-methacrylate | ≥ 7,000 | 5 µm | 40 Å | 2.0 x 150 mm | steel |
F6714011 | ODP2 HPG-2A | RP | - | Polyhydroxy-methacrylate | (guard) | 5 µm | - | 2.0 x 50 mm | steel |
F7622001 | ODP2 HP-4B | RP | - | Polyhydroxy-methacrylate | ≥ 3,500 | 5 µm | 40 Å | 4.6 x 50 mm | steel |
F7622002 | ODP2 HP-4D | RP | - | Polyhydroxy-methacrylate | ≥ 10,000 | 5 µm | 40 Å | 4.6 x 150 mm | steel |
F7622003 | ODP2 HP-4E | RP | - | Polyhydroxy-methacrylate | ≥ 17,000 | 5 µm | 40 Å | 4.6 x 250 mm | steel |
F6714010 | ODP2 HPG-4A | RP | - | Polyhydroxy-methacrylate | (guard) | 5 µm | - | 2.0 x 50 mm | steel |
Product details
Product name | Maximum pressure | Maximum flow rate | Temperature range | pH range | Salt concentration | Shipping solvent | USP |
|---|---|---|---|---|---|---|---|
ODP2 HP-2B | 12 MPa (120 bar) | 0.3 mL/min | 20 to 60°C | 2 to 12 | ≤ 0.1 M | H2O/ACN=55/45 | L39 |
ODP2 HP-2D | 15 MPa (150 bar) | 0.3 mL/min | 20 to 60°C | 2 to 12 | ≤ 0.1 M | H2O/ACN=55/45 | L39 |
ODP2 HPG-2A | - | - | 20 to 60°C | 2 to 12 | ≤ 0.1 M | H2O/ACN=55/45 | L39 |
ODP2 HP-4B | 15 MPa (150 bar) | 1.5 mL/min | 20 to 60°C | 2 to 12 | ≤ 0.1 M | H2O/ACN=55/45 | L39 |
ODP2 HP-4D | 15 MPa (150 bar) | 1.5 mL/min | 20 to 60°C | 2 to 12 | ≤ 0.1 M | H2O/ACN=55/45 | L39 |
ODP2 HP-4E | 15 MPa (150 bar) | 1.0 mL/min | 20 to 60°C | 2 to 12 | ≤ 0.1 M | H2O/ACN=55/45 | L39 |
ODP2 HPG-4A | - | - | 20 to 60°C | 2 to 12 | ≤ 0.1 M | H2O/ACN=55/45 | L39 |