Symbolic image of polar compound analysis

HILIC (hydrophilic interaction liquid chromatography)

 

Polymer-based columns for the analysis of polar substances

in drugs, food or biological samples

Product overview

Shodex Asahipak NH2P Series.jpg

Asahipak NH2P-50 series

Polymer-based HILIC column with amino groups (-NH2)

  • For polar substances

  • Suitable for saccharides analysis using HILIC mode

  • Polymer-based packing material provides excellent chemical stability and minimum
    deterioration over extended time period

  • Easily regenerated by washing in an alkaline solution

  • Appropriate for ELSD, CAD, LC-MS/MS

  • Fulfills USP L82 requirement

HILICpak VG-50

Polymer-based HILIC columns with tertiary amino (-NR2) groups

  • Suitable for saccharide analysis using HILIC mode

  • Recovers reducing saccharides with high ratio (improved results for galactose, mannose, arabinose and xylose in comparison to Asahipak NH2P-50 series)

  • Best for melamine analysis

  • Appropriate for ELSD, CAD, LC-MS/MS

  • Steel and PEEK housings to avoid interaction

Shodex HILICpak Series.jpg
Shodex HILICpak Series.jpg

HILICpak VT-50

Polymer-based HILIC columns with quaternary ammonium (-NR3+) groups

  • Best for glyphosate analysis and phosphorylated sugars

  • Suitable for anionic substances (especially phosphate compounds) analysis using HILIC mode

  • Use of some eluents add ion exchange mode

  • Polymer-based packing material provides excellent chemical stability and minimum deterioration over an extended time period

  • Suitable for LC-MS/MS analysis

HILICpak VC-50

Polymer-based HILIC columns with carboxyl (-COO-) groups

  • Modified carboxyl group is suitable for cationic substance analysis including amines

  • The dominant separation mode is RP or IEX rather than HILIC mode

  • Best for aminoglycoside antibiotics, histamine/histidine, monoamine neurotransmitters and more

  • Suitable for LC-MS/MS analysis

Shodex HILICpak Series.jpg
Shodex HILICpak Series.jpg

HILICpak VN-50

Polymer-based HILIC columns with diol (-OH) groups

  • Best for oligosaccharides and oligonucleotides

  • Suitable for oligomer separation which is not possible by SEC column or conventional HILIC columns

  • The modified diol groups on the packing material create the HILIC mode

Tutorial video