Product information

MSpak GF-4A

• Pretreatment column for column switching method

• High protein removal rate

• Removes surfactants well but is not suitable for trapping hydrophilic substances

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CLNpak EV Series

• GPC Clean-up columns

• Suitable for fractionation of residual pesticides in foods

• EV-2000 AC is used in Shoku-An No. 0124001 (January 24th, 2005, Japan) of the Pharmaceutical and Food Safety Bureau, MHLW, Section 2 “Simultaneous GC/MS (LC/MS) Analyses of Agricultural Chemicals in Livestock and Marine Products”.

• EV2000AC-12F is used in Shoku-An No. 0226 (February 26th, 2015, Japan) of the Pharmaceutical and Food Safety Bureau, MHLW, Section 2 “LC/MS Analyses of Agricultural Chemicals in Livestock and Marine Products”.

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Recently, the analysis of pesticides residues in many types of foods have become more important because of the increasing demand from EPA regulatory agencies.

The GPC (Gel Permeation Chromatography) clean-up method is widely used to remove lipids, polymers, pigments and other high molecular weight compounds from a wide range of sample matrices including food, tissues, grains, plants and environmental samples. Using this method combined with GC/MS, GC or HPLC, it is possible to detect many pesticides residues with good reproducibility in a relatively short period of time.

Dichloromethane has been used as an eluent for GPC clean-up, but as it may itself cause environmental pollution. To overcome this, the possibility of using a non-halogenated solvent such as ethyl acetate/cyclohexane as eluent was tested recently, but compared with dichloromethane the separation efficiency was inferior.

CLNpak EV-2000 series for GPC clean-up is developed to be used with non-halogenated solvents such as ethyl acetate/cyclohexane as the eluent. Using such solvents, EV-2000 series can obtain almost the same results when dichloromethane is used. This is the unique feature of EV-2000 series.